Sam E For Depression-S-adenosyl-L-methionine, known as SAM-e, is a compound that supports immune function and also helps with the production of brain chemicals called neurotransmitters, that of serotonin. It also maintains cell membranes., is involved in heart function, synthesis of collagen and bone health.
Sam-e was first discovered in 1952 and became available as a dietary supplement in 1999. This supplement has been used to manage the symptoms of anxiety due to SAM – Frankie’s role in producing and break down serotonin, dopamine, and norepinephrine.
If using SAM-e for anxiety, supplements can be taken in different forms, such as tablets, enteric coated, salute Tablets capsules and liquids. The dose of these supplements vary, with some product offers features 200 mg per serving and others 400 mg or 500 mg per serving. Some products offer 1.500 mg per serving.
Sam-e for anxiety and depression
How SAM-e affect anxiety and mood? This amino acid is involved in the synthesis of neurotransmitters regulate mood. Very low levels of SAM-e has been detected in the cerebrospinal fluid (CSF) patients experienced depression.
Sam-e is involved in pathways that lead to spending on serotonin, dopamine, and norepinephrine.
This line begins with folate, which is converted via the methylenetetrahydrofolate reductase (MTHFR) for 5-methyltetrahydrofolate (5-MTHF) and homocysteine.
5-MTHF and homocysteine converted through methyl synthase for L-methionine. L-methionine is then converted to SAM-e, which is a methyl donor in the synthesis of serotonin, dopamine, and norepinephrine.
Have adequate levels of these neurotransmitters is associated with depression and anxiety, according to a 2002 Review published in the American Journal of Clinical Nutrition.
Sam-e supplements have been used to manage panic attacks, reduce the level of stress in people with anxiety and improve cognitive function in people with depression or other mood disorders.
They have also been used to improve their sleep with sleep problems due to depression or anxiety. For those with anxiety and panic attacks, SAM-e supplements may help correct an imbalance in serotonin, which can help alleviate the symptoms of anxiety and panic attacks.
Consumers should note that the FDA has not approved the supplement SAM-e for the treatment of anxiety. In terms of effectiveness, not natural medicines comprehensive Database is given a value of SAM-e supplements for anxiety because of lack of research conducted to date.
How to take SAM-e for anxiety disorders
Sam-e supplements can be purchased online at Amazon and other leading retailers. There is a standard does have been determined for these products and manufacturers are not allowed to promote or formulate their supplements for the treatment of anxiety in the United States.
Consumers with anxiety should check with their doctor to make sure the supplement is safe to take and to know what dose to use. Your doctor may recommend supplements or other alternative treatment.
In General, those who take SAM-e product should start with a low dose and gradually work up to higher dosages. This helps reduce the risk of side effects. With the University of Maryland Medical Center recommends starting with a dose of 200 mg and increases the amount of the dose slowly.
High doses can increase the risk of side effects. Never take more than the recommended amount.