Splenda says it’s safe for diabetics. Yes, it is low in calories, but among other things.. (Completely artificial, as the body processes it, fillers etc.) Sucralose on his own seems to have a GI of zero, but that’s not the GI of Splenda.
MWSnap453 Is Splenda Safe For Diabetics
The fact is that Splenda contains Sucralose, but also includes two other sugars: Dextrose and Maltodextrin. And these sugars each have a GI of 100 & 130. Splenda has a GI of 80! Table sugar only has 65. If you don’t know about GI, here’s a great excerpt from the article.

The glycemic index (GI) is a ranking of carbohydrates on a scale from 0 to 100, depending on the extent to which they increase blood sugar levels after consumption. Foods with a high GI are those that are quickly digested and absorbed and lead to significant fluctuations in blood glucose levels. Low-GI foods produce a gradual increase in blood glucose and insulin levels due to their slow digestion and absorption and have proven health benefits.

It has been shown that low GI nutrition improves both glucose and fat levels in people with diabetes (type 1 and type 2). They have advantages for weight control because they help to control appetite and delay hunger. Low GI diets also reduce insulin levels and insulin resistance. “